Advances in Pharmacology and Therapeutics Journal

Advances in Pharmacology and Therapeutics Journal

Rapidly progressive dementia and severe awake bruxism resistance to treatment: An unresolved challenge to treatment

Document Type : Case study

Authors
Reza Bidaki
zahra Alizadeh
Milad Sadeghi
Ali Zare
10.18502/aptj.v1i2.8669
Abstract
Background: Bruxism is a chief complaint in some patients with dementia, but there is no clear guideline for its management.Here, we presented a case with awake bruxism.
Case presentation: This case report study described an 88-year-old woman with severe rapidly progressive dementia (RPD) and awake bruxism, which was improved with discontinuation of sertraline, quetiapine, gabapentin, and resumption of trazodone.
Conclusion: In this case study, despite taking drugs from different classifications for bruxism treatment, no improvement was seen. Bruxism is an important and challenging condition for physicians and caregivers in dementia patients. Although  bruxism needs serious treatment, there is no suitable and well-defined treatment for this disorder. Further studies are needed to suggest an efficient drug for the management of bruxism. 
Keywords
Bruxism
Dementia
Resistance to treatment