Shahid Sadoughi University of Medical Sciences https://en.ssu.ac.ir/publications/ Advances in Pharmacology and Therapeutics Journal 2783-3445 2 1 2022 09 01 Acute Trismus Follow Benzodiazepine Discontinuation in a Rural Addicted Patient 11 13 299 10.18502/aptj.v2i1.10652 EN Mahsa Motamed Yekta Rameshi Fatemeh Saghafi Sina Taherzadeh Borujeni Reza Bidaki Journal Article 2022 04 03 in this study it was introduced a 34-year-old married man from a small city in the Southeastern area of Iran who was referred to a psychiatrist because of the restriction of the range of his jaw motion.<br />The patient could not open his mouth within the normal range (35 to 55 mm; 3-finger wide). He felt intolerable pain and had talking problems, eating, swallowing, and was highly emotional. Three finger test was positive. He had a history of using opium (1 mg per day) and clonazepam (1 mg every night) from 10 years ago. He had a history of sudden drug withdrawal and has replaced the opium with 20 mg of methadone tablet. He had no personal or family history of other illnesses. In his neurological checkup, a painful condition restricted optimal mandibular movement caused by masticating muscle spasms. https://aptjournal.ssu.ac.ir/article_299_b2f87fed5fb4f28562f9817d74a1928e.pdf